Everyone aspires to have a fit, lean, and healthy body. This healthy trend has become more relevant with the rise in bodybuilding activities such as going to the gym, playing, and consuming supplements. If you look to have bulking and lean muscle gain, you have landed in the right place. We will talk about the famous testolone, which also goes by the name of RAD140. For starters, it is an unapproved drug, yet has found widespread application, especially among athletes and bodybuilders community, thanks to its various benefits. Though it has become quite popular, it is best to know all about it before using it for yourself. If you want to learn about this drug, keep reading the blog.
What is Testolone?
It is a new investigational drug that belongs to selective androgen receptor modulators, also known as SARMs, a class of compounds that bind to different androgen receptors of different body areas. Usually, the SARMs interact with naturally occurring body androgens such as androstenedione, testosterone, and dihydrotestosterone in muscles, tissues, and bones. Testosterone in the body and SARMs are known to produce similar effects as they work on the same receptor, thus resulting in improved muscles and bones. Therefore, the drug can be considered as an anabolic steroid without any harmful effects associated with it.
Now that we know what testolone is, let us learn how it works on the body to bring out the best results.
Mechanism of testolone
With selective stimulation of the body’s androgen receptors, testolone functions as it targets the muscle and bone-based receptors. Many claims that the compound stimulates muscle growth by developing muscle cells and proteins. Though the selection interaction of the SARM compounds has not been fully understood, many researchers claim that they target and activate different proteins selectively except testosterone. This thus results in the activation of specific androgen receptors, primarily in the muscles. The testolone’s chemical structure is quite different from steroid hormones. Therefore, the path that converts the steroid hormones into other hormones doesn’t seem to work on RAD140.
Since we now know how the compound works on the body, let us walk through the benefit it offers, due to which it has garnered so much attention.
Potential benefits of using testolone
According to various anecdotal evidence stated by people testolone, there are different types of experiences felt. Let us learn about it:
- Increase in muscle mass
Thanks to the purported muscle-building effects, it helps build muscle and is a popular choice in the bodybuilding community. According to various research, these SRMs help increase muscle growth without producing any unwanted side effects of regular steroids. Having said this, the scientific evidence behind the testolone’s application is scant.
- Treatment of breast cancer
Androgen and estrogen receptor-positive (AR/ER+) is a common form of breast cancer. These forms are sensitive to hormones, and the medication that affects receptors such as SARMs may potentially fight cancer cells. In a cell study, testolone inhibits the AR/ER+ breast cancer by stopping the estrogen’s effects. The RAD140 appears to be explicitly suppressing the ESR1 gene.
- Promotes Weight loss
Although this form of SARM is studied in monkeys, many believe it reduces body fat. There is one study done on monkeys. It showed increased lean muscle; however, its effect on body fat is unclear.
- Improvement in brain health
Androgens play a key role in protecting the brain, promoting cell growth, decreasing amyloid-beta accumulation, and improving memory. Amyloid-beta plaque is one of the main reasons for Alzheimer’s disease. RAD140 has proven to be effective against neurotoxins.
Apart from these benefits, there is much evidence that indicates the enhancement of sexual performance. However, it can be associated with its testosterone-mimicking effects.
These are a few potential benefits of using the compounds. However, it is recommended to use them in appropriate quantities. Let us learn about its proper dosage:
What is the appropriate amount of dose for testolone?
According to various experts, 0.1mg/kg of the compound can exhibit its effect on the body; thus, it all comes down to the users’ experience level. If the user is taking it for the first time, the recommended dose is eight to ten mg of the compound every day, and it should continue for the next six to eight weeks. For people with experience, the recommended dose is 20 mg per day for a course of eight to ten weeks. If a person wants to consume it twice a day, they can divide the intake quantity and take it twice.
Those who have more experience and are professional bodybuilders can consume about 20 mg once a day for about ten weeks.
If anyone desires to consume it more than once a day, they can divide the recommended intake quantity and consume it twice per day. However, the consumption of the compound should not exceed ten weeks, lest the body might start experiencing negative impacts. Before consumption, it is best to have detailed knowledge about the potential side effects.
Potential side effects of testolone
Though there has been studies and research that indicate the potential benefits of testolone, however, there have been various anecdotal experiences showing certain side effects that include;
- Loss of hair.
- Sudden mood swings and fatigue.
- Decrease in testosterone level.
- Breast tenderness in women and growth in men.
- Anxiety, nausea, vomiting, and depression.
- Bald patches in men.
- Improper growth of body hair in women.
There isn’t any human study citing the long-term risk of the product. Even the safety profile and full side effects are unknown to date. Along with that, there is no specific study regarding the dosage.
Conclusion-
Testolone is used as a supplement by many athletes and bodybuilders; however, it is unapproved. Though the application of RAD140 has many potential benefits, there are limited proofs or studies that explore its usage in humans. It is because the test is done on monkeys and rats. Thus, we cannot confidently say how safe it is or even if it works; therefore, it is upon the users’ discretion to use it.
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